Drug	Typical Dosing

Amoxicillin Amoxil^®, Trimox^® Generics available Pregnancy: B; Lactation: Safe Caps: 250 mg, 500 mg Tabs: 500 mg, 875 mg Chewable Tab: 125 mg,  250 mg, Oral Susp: 125 mg/5 mL 250 mg/5 mL 200 mg/5 mL 400 mg/5 mL

Neonates and infants ≤3 months: 20-30 mg/kg/day in divided doses Q12H. Children >3 months: 25-50 mg/kg/day (max 2-3 g/day) in divided doses Q8H or Q12H. 250 mg/5 mL at 50 mg/kg/day 10 kg (22 lb) = 1 tsp (5 mL) Q12H 15 kg (33 lb) = 1 tsp (5 mL) Q8H 20 kg (44 lb) = 2 tsp (10 mL) Q12H >25 kg = Use adult dose. Adult: 250-500 mg PO Q8H or 500-875 mg PO Q12H. Food: May take with or without meals. Important side effects: Nausea, vomiting, diarrhea, agitation, seizures, rash, bleeding abnormalities, decreased WBC count, drug fever, superinfection. Caution: May cause nonallergic maculopapular rash, especially in patients with viral infection, infectious mononucleosis, or acute lymphocytic leukemia. Reduce dose in renal disease: CrCl 10-30 mL/min administer every 12 hours CrCl <10 mL/min administer every 24 hours